Short term and Long term results from 19,000 patients
Gianfranco
Cappello*, Antonella Franceschellim Annalisa Cappello and Paolo De Luca
Clinical Nutrition Service of the
Department of Surgery Paride Stefanini, University of Rome La Sapienze, Rome,
Italy
Nutrition & Metabolism 2012, 9:96
doi:10.1186/1743-7075-9-96 © 2012 Cappello et al.; licencse BioMed Central Ltd.
Abstract
Background
Only protein
diet has been used successfully to prevent loss of lean body mass first in
post-surgical and then in obese patients. We studied overweight and obese
patients receiving short treatments of an exclusively protein-based nutritional
solution as 24-hours enteral infusion.
19,036 patients
age 44.3±13, M:F = 2:5) with an initial body mass index of 36.5 ± 7.1
inderwent 10-day
cycles of enteral nutrition through a fine nasogastric tube. The nutritional
solution consisted solely of 50-65g of proteins, plus vitamins and
electrolytes. The 24-hour infusion was controlled with a small portable pump.
Before and after each 10-day cycle body composition was checked with a Handy
3000 impedance analyzer. At the onset of treatment, average fat mass was 40.9 ±
12.8Kg while body cell mass was 42.7 ± 7.2Kg in males and 27.4 ± 4.6Kg in
females.
Results
After an average
of 2.5 cycles the patients lost 10.2 ± 7.0Kg of body weight., 5.8 ± 5.5Kg of
fat mass and 2.2 ± 3.3Kg of body cell mass. No significant adverse effects were
recorded except asthenia and constipation which were easily controlled with
therapy. Long-term results were obtained from 15,444 patients and after an
average of 362 ± 296 days we found a mean weight regain of 15.4%.
Conclusion
Ketogenic
Enteral Nutrition treatment of over 19,000 patients induced a rapid 10% weight loss
57% of which was Fat Mass. No Significant adverse effects were found. The
treatment is safe, fast, and inexpensive and has good one-year results for
weight maintenance.
The KEN program
founded in Italy and proven effective by over 57,000 participants, is a
non-surgical procedure that feeds the body 24 hours a day for 10 days. This “Protein
sparing” nutritional is a serious works like no other, targeting fat while
preserving lean body mass. Ketogenic Enteral Nutrition is a serious,
non-surgical, low cost solution. It is not a vanity product designed to make
users look glamorous, it’s for obese men and women who need real help and
achievable, healthy outcomes. KEN is looking for physicians with patients who
are not yet fit enough for surgery or for whom surgery is not the best option.
CONTACT
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